A carregar...
Carboxyl Terminated PAMAM-SN38 Conjugates: Synthesis, Characterization, and In vitro Evaluation
In the present work, carboxyl terminated PAMAM G-3.5 was covalently attached to SN38 via glycine and β-alanine spacers. The conjugates were stable at pH 7.4 and moderately hydrolyzed in cell culture media and rat plasma. Similar to SN38 but to a lesser extent, both conjugates inhibited proliferation...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197241/ https://ncbi.nlm.nih.gov/pubmed/20836544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100094z |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|