Retinoic Acid Inhibits HIV-1–Induced Podocyte Proliferation through the cAMP Pathway

HIV-associated nephropathy is characterized by renal podocyte proliferation and dedifferentiation. This study found that all-trans retinoic acid (atRA) reverses the effects of HIV-1 infection in podocytes. Treatment with atRA reduced cell proliferation rate by causing G1 arrest and restored the expr...

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Autors principals: He, John Cijiang, Lu, Ting-Chi, Fleet, Margaret, Sunamoto, Masaaki, Husain, Mohammad, Fang, Wei, Neves, Susana, Chen, Yibang, Shankland, Stuart, Iyengar, Ravi, Klotman, Paul E.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197239/
https://ncbi.nlm.nih.gov/pubmed/17182884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2006070727
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