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Structural basis of the Ca(2+) inhibitory mechanism of Drosophila Na(+)/Ca(2+) exchanger CALX and its modification by alternative splicing
The Na(+)/Ca(2+) exchanger CALX promotes Ca(2+) efflux in Drosophila sensory neuronal cells to facilitate light-mediated Ca(2+) homeostasis. CALX activity is negatively regulated by specific Ca(2+) interaction within its two intracellular Ca(2+) regulatory domains CBD1 and CBD2, yet how the Ca(2+) b...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197212/ https://ncbi.nlm.nih.gov/pubmed/22000518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.07.008 |
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