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Bioenergetic Consequences of PINK1 Mutations in Parkinson Disease
BACKGROUND: Mutations of the gene for PTEN-induced kinase 1 (PINK1) are a cause of familial Parkinson's disease (PD). PINK1 protein has been localised to mitochondria and PINK1 gene knockout models exhibit abnormal mitochondrial function. The purpose of this study was to determine whether cells...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197155/ https://ncbi.nlm.nih.gov/pubmed/22043288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025622 |
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