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GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors

Serum butyrylcholinesterase (BCHE) activity is associated with obesity, blood pressure and biomarkers of cardiovascular and diabetes risk. We have conducted a genome-wide association scan to discover genetic variants affecting BCHE activity, and to clarify whether the associations between BCHE activ...

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書誌詳細
主要な著者: Benyamin, Beben, Middelberg, Rita P., Lind, Penelope A., Valle, Anne M., Gordon, Scott, Nyholt, Dale R., Medland, Sarah E., Henders, Anjali K., Heath, Andrew C., Madden, Pamela A.F., Visscher, Peter M., O'Connor, Daniel T., Montgomery, Grant W., Martin, Nicholas G., Whitfield, John B.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196893/
https://ncbi.nlm.nih.gov/pubmed/21862451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr375
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