GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors

Serum butyrylcholinesterase (BCHE) activity is associated with obesity, blood pressure and biomarkers of cardiovascular and diabetes risk. We have conducted a genome-wide association scan to discover genetic variants affecting BCHE activity, and to clarify whether the associations between BCHE activ...

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Detalhes bibliográficos
Main Authors: Benyamin, Beben, Middelberg, Rita P., Lind, Penelope A., Valle, Anne M., Gordon, Scott, Nyholt, Dale R., Medland, Sarah E., Henders, Anjali K., Heath, Andrew C., Madden, Pamela A.F., Visscher, Peter M., O'Connor, Daniel T., Montgomery, Grant W., Martin, Nicholas G., Whitfield, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196893/
https://ncbi.nlm.nih.gov/pubmed/21862451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr375
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