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Functional and physical interaction between the mismatch repair and FA-BRCA pathways

Fanconi anemia (FA) is a rare genetic disorder characterized by bone marrow failure and an increased risk for leukemia and cancer. Fifteen proteins thought to function in the repair of DNA interstrand crosslinks (ICLs) comprise what is known as the FA-BRCA pathway. Activation of this pathway leads t...

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Bibliographic Details
Main Authors: Williams, Stacy A., Wilson, James B., Clark, Allison P., Mitson-Salazar, Alyssa, Tomashevski, Andrei, Ananth, Sahana, Glazer, Peter M., Semmes, O. John, Bale, Allen E., Jones, Nigel J., Kupfer, Gary M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196888/
https://ncbi.nlm.nih.gov/pubmed/21865299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr366
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