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Functional and physical interaction between the mismatch repair and FA-BRCA pathways
Fanconi anemia (FA) is a rare genetic disorder characterized by bone marrow failure and an increased risk for leukemia and cancer. Fifteen proteins thought to function in the repair of DNA interstrand crosslinks (ICLs) comprise what is known as the FA-BRCA pathway. Activation of this pathway leads t...
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Main Authors: | , , , , , , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Oxford University Press
2011
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196888/ https://ncbi.nlm.nih.gov/pubmed/21865299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr366 |
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