Structure-activity Relationships for Hydroxylated Polychlorinated Biphenyls as Inhibitors of the Sulfation of Dehydroepiandrosterone Catalyzed by Human Hydroxysteroid Sulfotransferase SULT2A1

Polychlorinated biphenyls (PCBs) are persistent worldwide pollutants that are of concern due to their bioaccumulation and health effects. Metabolic oxidation of PCBs results in the formation of hydroxylated metabolites (OHPCBs). Among their biological effects, OHPCBs have been shown to alter the met...

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Main Authors: Ekuase, Edugie J., Liu, Yungang, Lehmler, Hans-Joachim, Robertson, Larry W., Duffel, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196794/
https://ncbi.nlm.nih.gov/pubmed/21913674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200260h
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