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Physicochemical properties of hydroxylated polychlorinated biphenyls aid in predicting their interactions with rat sulfotransferase 1A1 (rSULT1A1)

Hydroxylated metabolites of polychlorinated biphenyls (OHPCBs) interact with rat sulfotransferase 1A1 (rSULT1A1) as substrates and inhibitors. Previous studies have shown that there are complex and incompletely understood structure-activity relationships governing the interaction of rSULT1A1 with th...

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Detalhes bibliográficos
Main Authors: Liu, Yungang, Lehmler, Hans-Joachim, Robertson, Larry W., Duffel, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032042/
https://ncbi.nlm.nih.gov/pubmed/21130751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.11.009
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