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KRN/I-A(g7) Mouse Arthritis Is Independent of Complement C3
BACKGROUND: KRN/I-A(g7) (KxB/N) is a mouse model of inflammatory arthritis, which resembles human rheumatoid arthritis. Arthritis in these animals is caused by autoreactivity to a ubiquitously expressed autoantigen, glucose-6 phosphate isomerase. Tolerance is broken at both the T cell and B cell lev...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196781/ https://ncbi.nlm.nih.gov/pubmed/21732014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-011-9562-2 |
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