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Indole alkaloids: dihydroteleocidin B, teleocidin, and lyngbyatoxin A as members of a new class of tumor promoters.

Dihydroteleocidin B, which is a derivative of teleocidin from Streptomyces, showed potent tumor-promoting activity in vivo when painted on mouse skin. Although the chemical structure of dihydroteleocidin B is entirely different from those of phorbol esters, the tumor-promoting activity of dihydrotel...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Fujiki, H, Mori, M, Nakayasu, M, Terada, M, Sugimura, T, Moore, R E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319675/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6791164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.6.3872
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