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Prediction of protein antigenic determinants from amino acid sequences.

A method is presented for locating protein antigenic determinants by analyzing amino acid sequences in order to find the point of greatest local hydrophilicity. This is accomplished by assigning each amino acid a numerical value (hydrophilicity value) and then repetitively averaging these values alo...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Hopp, T P, Woods, K R
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1981
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319665/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6167991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.6.3824
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