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Prediction of protein antigenic determinants from amino acid sequences.

A method is presented for locating protein antigenic determinants by analyzing amino acid sequences in order to find the point of greatest local hydrophilicity. This is accomplished by assigning each amino acid a numerical value (hydrophilicity value) and then repetitively averaging these values alo...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hopp, T P, Woods, K R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1981
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319665/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6167991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.6.3824
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