Genome-wide CTCF distribution in vertebrates defines equivalent sites that can aid in the identification of disease-associated genes

Many genomic alterations associated to human diseases localize in non-coding regulatory elements located far from the promoters they regulate, making the association of non-coding mutations or risk associated variants to target genes challenging. The range of action of a given set of enhancers is th...

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Detalhes bibliográficos
Main Authors: Martin, David, Pantoja, Cristina, Miñán, Ana Fernández, Valdes-Quezada, Christian, Moltó, Eduardo, Matesanz, Fuencisla, Bogdanovic, Ozren, de la Calle-Mustienes, Elisa, Domínguez, Orlando, Taher, Leila, Furlan-Magaril, Mayra, Alcina, Antonio, Cañón, Susana, Fedetz, María, Blasco, María A., Pereira, Paulo S., Ovcharenko, Ivan, Recillas-Targa, Félix, Montoliu, Lluís, Manzanares, Miguel, Guigó, Roderic, Serrano, Manuel, Casares, Fernando, Gómez-Skarmeta, José Luis
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196567/
https://ncbi.nlm.nih.gov/pubmed/21602820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2059
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