Generation of Replication-Defective Virus-Based Vaccines That Confer Full Protection in Sheep against Virulent Bluetongue Virus Challenge

The reverse genetics technology for bluetongue virus (BTV) has been used in combination with complementing cell lines to recover defective BTV-1 mutants. To generate a potential disabled infectious single cycle (DISC) vaccine strain, we used a reverse genetics system to rescue defective virus strain...

詳細記述

保存先:
書誌詳細
主要な著者: Matsuo, Eiko, Celma, Cristina C. P., Boyce, Mark, Viarouge, Cyril, Sailleau, Corinne, Dubois, Eric, Bréard, Emmanuel, Thiéry, Richard, Zientara, Stéphan, Roy, Polly
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2011
主題:
Pathogenesis and Immunity
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196398/
https://ncbi.nlm.nih.gov/pubmed/21795358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05412-11
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