Dissection of a Type I Interferon Pathway in Controlling Bacterial Intracellular Infection in Mice

Defense mechanisms against intracellular bacterial pathogens are incompletely understood. Our study characterizes a type I IFN-dependent cell-autonomous defense pathway directed against Legionella pneumophila, an intracellular model organism and frequent cause of pneumonia. We show that macrophages...

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Detalhes bibliográficos
Main Authors: Lippmann, Juliane, Müller, Holger, Naujoks, Jan, Tabeling, Christoph, Shin, Sunny, Witzenrath, Martin, Hellwig, Katharina, Kirschning, Carsten J., Taylor, Gregory A., Barchet, Winfried, Bauer, Stefan, Suttorp, Norbert, Roy, Craig R., Opitz, Bastian
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196383/
https://ncbi.nlm.nih.gov/pubmed/21790939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2011.01646.x
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