Chemical Genetics of Zipper-interacting Protein Kinase Reveal Myosin Light Chain as a Bona Fide Substrate in Permeabilized Arterial Smooth Muscle

Zipper-interacting protein kinase (ZIPK) has been implicated in Ca(2+)-independent smooth muscle contraction, although its specific role is unknown. The addition of ZIPK to demembranated rat caudal arterial strips induced an increase in force, which correlated with increases in LC(20) and MYPT1 phos...

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Main Authors: Moffat, Lori D., Brown, Shannon B. A., Grassie, Michael E., Ulke-Lemée, Annegret, Williamson, Laura M., Walsh, Michael P., MacDonald, Justin A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196122/
https://ncbi.nlm.nih.gov/pubmed/21880706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.257949
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