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Phosphorylation of Right Open Reading Frame 2 (Rio2) Protein Kinase by Polo-like Kinase 1 Regulates Mitotic Progression

Polo-like kinase 1 (Plk1) plays essential roles during multiple stages of mitosis by phosphorylating a number of substrates. Here, we report that the atypical protein kinase Rio2 is a novel substrate of Plk1 and can be phosphorylated by Plk1 at Ser-335, Ser-380, and Ser-548. Overexpression of Rio2 c...

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Bibliografske podrobnosti
Main Authors: Liu, Ting, Deng, Min, Li, Junhui, Tong, Xiaomei, Wei, Qian, Ye, Xin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196107/
https://ncbi.nlm.nih.gov/pubmed/21880710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.250175
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