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Phosphorylation of MCM3 Protein by Cyclin E/Cyclin-dependent Kinase 2 (Cdk2) Regulates Its Function in Cell Cycle
MCM2–7 proteins form a stable heterohexamer with DNA helicase activity functioning in the DNA replication of eukaryotic cells. The MCM2–7 complex is loaded onto chromatin in a cell cycle-dependent manner. The phosphorylation of MCM2–7 proteins contributes to the formation of the MCM2–7 complex. Howe...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220541/ https://ncbi.nlm.nih.gov/pubmed/21965652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.226464 |
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