The E-box Binding Factors Max/Mnt, MITF, and USF1 Act Coordinately with FoxO to Regulate Expression of Proapoptotic and Cell Cycle Control Genes by Phosphatidylinositol 3-Kinase/Akt/Glycogen Synthase Kinase 3 Signaling

Phosphatidylinositol (PI) 3-kinase/Akt signaling plays a critical role in cell proliferation and survival, partly by regulation of FoxO transcription factors. Previous work using global expression profiling indicated that inhibition of PI 3-kinase in proliferating cells led to induction of genes tha...

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Detalhes bibliográficos
Main Authors: Terragni, Jolyon, Nayak, Gauri, Banerjee, Swati, Medrano, Jose-Luis, Graham, Julie R., Brennan, James F., Sepulveda, Sean, Cooper, Geoffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196102/
https://ncbi.nlm.nih.gov/pubmed/21873430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246116
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