Transcriptional profiling of TLR-4/7/8-stimulated guinea pig splenocytes and whole blood by bDNA assay

Toll-like receptor (TLR) agonists are currently being examined as adjuvants for vaccines, with several lead candidates now in licensed products or in late-stage clinical development. Guinea pigs are widely used for preclinical testing of drugs and vaccines; however, evaluation of TLR agonists in thi...

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Autores principales: Ching, Lance K., Mompoint, Farah, Guderian, Jeffrey A., Picone, Alex, Orme, Ian M., Coler, Rhea N., Reed, Steven G., Baldwin, Susan L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196045/
https://ncbi.nlm.nih.gov/pubmed/21839740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.07.021
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