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Leptin Boosts Cellular Metabolism by Activating AMPK and the Sirtuins to Reduce Tau Phosphorylation and β-Amyloid in Neurons

Leptin is a pleiotropic hormone primarily secreted by adipocytes. A high density of functional Leptin receptors has been reported to be expressed in the hippocampus and other cortical regions of the brain, the physiological significance of which has not been explored extensively. Alzheimer’s disease...

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Bibliografski detalji
Glavni autori: Greco, Steven J., Hamzelou, Ashkan, Johnston, Jane M., Smith, Mark A., Ashford, J. Wesson, Tezapsidis, Nikolaos
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196043/
https://ncbi.nlm.nih.gov/pubmed/21945934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.09.050
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