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Leptin Boosts Cellular Metabolism by Activating AMPK and the Sirtuins to Reduce Tau Phosphorylation and β-Amyloid in Neurons

Leptin is a pleiotropic hormone primarily secreted by adipocytes. A high density of functional Leptin receptors has been reported to be expressed in the hippocampus and other cortical regions of the brain, the physiological significance of which has not been explored extensively. Alzheimer’s disease...

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Sonraí Bibleagrafaíochta
Main Authors: Greco, Steven J., Hamzelou, Ashkan, Johnston, Jane M., Smith, Mark A., Ashford, J. Wesson, Tezapsidis, Nikolaos
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196043/
https://ncbi.nlm.nih.gov/pubmed/21945934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.09.050
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