A Peptide Filtering Relation Quantifies MHC Class I Peptide Optimization

Major Histocompatibility Complex (MHC) class I molecules enable cytotoxic T lymphocytes to destroy virus-infected or cancerous cells, thereby preventing disease progression. MHC class I molecules provide a snapshot of the contents of a cell by binding to protein fragments arising from intracellular...

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Bibliographic Details
Main Authors: Dalchau, Neil, Phillips, Andrew, Goldstein, Leonard D., Howarth, Mark, Cardelli, Luca, Emmott, Stephen, Elliott, Tim, Werner, Joern M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195949/
https://ncbi.nlm.nih.gov/pubmed/22022238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002144
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