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Selector function of MHC I molecules is determined by protein plasticity

The selection of peptides for presentation at the surface of most nucleated cells by major histocompatibility complex class I molecules (MHC I) is crucial to the immune response in vertebrates. However, the mechanisms of the rapid selection of high affinity peptides by MHC I from amongst thousands o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bailey, Alistair, Dalchau, Neil, Carter, Rachel, Emmott, Stephen, Phillips, Andrew, Werner, Jörn M., Elliott, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224517/
https://ncbi.nlm.nih.gov/pubmed/26482009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14928
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