Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional ‘detour’ in the hemisected spinal cord

To encourage re-establishment of functional innervation of ipsilateral lumbar motoneurons by descending fibers after an intervening lateral thoracic (T10) hemisection (Hx), we treated adult rats with the following agents: (i) anti-Nogo-A antibodies to neutralize the growth-inhibitor Nogo-A; (ii) neu...

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Bibliographic Details
Main Authors: Schnell, Lisa, Hunanyan, Arsen S, Bowers, William J, Horner, Philip J, Federoff, Howard J, Gullo, Miriam, Schwab, Martin E, Mendell, Lorne M, Arvanian, Victor L
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2011
Subjects:
Neurosystems
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195885/
https://ncbi.nlm.nih.gov/pubmed/21995852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2011.07862.x
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