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Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function

BACKGROUND: APP expression misregulation can cause genetic Alzheimer's disease (AD). Recent evidences support the hypothesis that polymorphisms located in microRNA (miRNA) target sites could influence the risk of developing neurodegenerative disorders such as Parkinson's disease (PD) and f...

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Detalhes bibliográficos
Main Authors: Delay, Charlotte, Calon, Frédéric, Mathews, Paul, Hébert, Sébastien S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195754/
https://ncbi.nlm.nih.gov/pubmed/21982160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-70
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