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Identification of a Cytochrome P4502E1/Bid/C1q-dependent Axis Mediating Inflammation in Adipose Tissue after Chronic Ethanol Feeding to Mice

Chronic, heavy alcohol exposure results in inflammation in adipose tissue, insulin resistance, and liver injury. Here we have identified a CYP2E1/Bid/C1q-dependent pathway that is activated in response to chronic ethanol and is required for the development of inflammation in adipose tissue. Ethanol...

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Detalhes bibliográficos
Main Authors: Sebastian, Becky M., Roychowdhury, Sanjoy, Tang, Hui, Hillian, Antoinette D., Feldstein, Ariel E., Stahl, Gregory L., Takahashi, Kazue, Nagy, Laura E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195631/
https://ncbi.nlm.nih.gov/pubmed/21856753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254201
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