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Unbinding of Hyaluronan Accelerates the Enzymatic Activity of Bee Hyaluronidase
Hyaluronan (HA), a polymeric glycosaminoglycan ubiquitously present in higher animals, is hydrolyzed by hyaluronidases (HAases). Here, we used bee HAase as a model enzyme to study the HA-HAase interaction. Located in close proximity to the active center, a bulky surface loop, which appears to obstru...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3195588/ https://ncbi.nlm.nih.gov/pubmed/21840987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.263731 |
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