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Akt Fine-tunes NF-κB-dependent Gene Expression during T Cell Activation

Activation of the NF-κB signaling pathway is critical for leukocyte activation and development. Although previous studies suggested a role for the Akt kinase in coupling the T cell antigen receptor and CD28 to NF-κB activation in T cells, the nature of the role of Akt in this pathway is still unclea...

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Autors principals: Cheng, Jing, Phong, Binh, Wilson, David C., Hirsch, Raphael, Kane, Lawrence P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195567/
https://ncbi.nlm.nih.gov/pubmed/21862580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259549
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