Biodistribution and Tumor Imaging of an Anti-CEA Single Chain Antibody-Albumin Fusion Protein

Albumin fusion proteins have demonstrated the ability to prolong the in vivo half-life of small therapeutic proteins/peptides in the circulation and thereby potentially increase their therapeutic efficacy. To evaluate if this format can be employed for antibody-based imaging, an anti-carcinoembryoni...

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Hauptverfasser: Yazaki, Paul J., Kassa, Thewodros, Cheung, Chia-wei, Crow, Desiree M., Sherman, Mark A., Bading, James R., Anderson, Anne-Line J., Colcher, David, Raubitschek, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195408/
https://ncbi.nlm.nih.gov/pubmed/18312824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2007.10.010
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