A Methodology for Simultaneous Fluorogenic Derivatization and Boronate Affinity Enrichment of 3-Nitrotyrosine Containing Peptides

We synthesized and characterized a new tagging reagent, (3R,4S)-1-(4-(aminomethyl)phenylsulfonyl)pyrrolidine-3,4-diol (APPD), for the selective fluorogenic derivatization of 3-nitrotyrosine (3-NT) residues in peptides (after reduction to 3-aminotyrosine) and affinity enrichment. The synthetic 3-NT-c...

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Bibliographic Details
Main Authors: Dremina, Elena S., Li, Xiaobao, Galeva, Nadezhda A., Sharov, Victor S., Stobaugh, John F., Schöneich, Christian
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195362/
https://ncbi.nlm.nih.gov/pubmed/21855526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.07.024
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