Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum

Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder in which calcification of connective tissue leads to pathology in skin, eye and blood vessels. PXE is caused by mutations in ABCC6. High expression of this transporter in the basolateral hepatocyte membrane suggests that it secretes a...

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Main Authors: Gorgels, Theo G. M. F., Waarsing, Jan H., Herfs, Marjolein, Versteeg, Daniëlle, Schoensiegel, Frank, Sato, Toshiro, Schlingemann, Reinier O., Ivandic, Boris, Vermeer, Cees, Schurgers, Leon J., Bergen, Arthur A. B.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2011
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195265/
https://ncbi.nlm.nih.gov/pubmed/21725681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-011-0782-y
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