A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine

We examined the safety, immunogenicity and efficacy of a prime-boost vaccination regime involving two poxvirus malaria subunit vaccines, FP9-PP and MVA-PP, expressing the same polyprotein consisting of six pre-erythrocytic antigens from Plasmodium falciparum. Following safety assessment of single do...

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Bibliografiset tiedot
Päätekijät: Porter, David W., Thompson, Fiona M., Berthoud, Tamara K., Hutchings, Claire L., Andrews, Laura, Biswas, Sumi, Poulton, Ian, Prieur, Eric, Correa, Simon, Rowland, Rosalind, Lang, Trudie, Williams, Jackie, Gilbert, Sarah C., Sinden, Robert E., Todryk, Stephen, Hill, Adrian V.S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier Science 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195259/
https://ncbi.nlm.nih.gov/pubmed/21501642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.03.083
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