MIG (CXCL9) is a more sensitive measure than IFN-γ of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines

For many years the IFN-γ ex vivo ELISPOT has been a major assay for assessing human T-cell responses generated by malaria vaccines. The ELISPOT assay is a sensitive assay, but an imperfect correlate of protection against malaria. Monokine induced by gamma (MIG), or CXCL9, is a chemokine induced by I...

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Main Authors: Berthoud, Tamara K., Dunachie, Susanna J., Todryk, Stephen, Hill, Adrian V.S., Fletcher, Helen A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2009
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648876/
https://ncbi.nlm.nih.gov/pubmed/18952093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2008.09.021
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