A shift of the TOR adaptor from Rictor towards Raptor by semaphorin in C. elegans

The target of rapamycin (TOR), a central regulator for cell growth and metabolism, resides in the two functionally distinct complexes TORC1 and TORC2, which are defined by their adaptors Raptor and Rictor, respectively. How the formation of the two TORCs is orchestrated remains unclear. Here we show...

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Bibliografiske detaljer
Main Authors: Nukazuka, Akira, Tamaki, Shusaku, Matsumoto, Kunihiro, Oda, Yoichi, Fujisawa, Hajime, Takagi, Shin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195255/
https://ncbi.nlm.nih.gov/pubmed/21952218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1495
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