Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.

The rates of spontaneous mutation to 6-thioguanine resistance were determined in fibroblasts derived from normal and two Bloom syndrome individuals (GM 2548 and GM 1492). Two methods were utilized to determine the rates. Method I obtained the spontaneous mutation rate from the increase in the mutati...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Warren, S T, Schultz, R A, Chang, C C, Wade, M H, Trosko, J E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1981
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319514/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6942420/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.5.3133
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