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Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.

The rates of spontaneous mutation to 6-thioguanine resistance were determined in fibroblasts derived from normal and two Bloom syndrome individuals (GM 2548 and GM 1492). Two methods were utilized to determine the rates. Method I obtained the spontaneous mutation rate from the increase in the mutati...

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Autores principales: Warren, S T, Schultz, R A, Chang, C C, Wade, M H, Trosko, J E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1981
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC319514/
https://ncbi.nlm.nih.gov/pubmed/6942420
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