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Dll4-Notch signaling as a therapeutic target in tumor angiogenesis

Tumor angiogenesis is an important target for cancer therapy, with most current therapies designed to block the VEGF signaling pathway. However, clinical resistance to anti-VEGF therapy highlights the need for targeting additional tumor angiogenesis signaling pathways. The endothelial Notch ligand D...

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Detalhes bibliográficos
Main Authors: Kuhnert, Frank, Kirshner, Jessica R, Thurston, Gavin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195111/
https://ncbi.nlm.nih.gov/pubmed/21923938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-3-20
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