SMB-1, a Novel Subclass B3 Metallo-β-Lactamase, Associated with ISCR1 and a Class 1 Integron, from a Carbapenem-Resistant Serratia marcescens Clinical Isolate

A carbapenem-resistant Serratia marcescens strain, 10mdr148, was identified in a Japanese hospital in 2010. The carbapenem resistance of this strain was attributed to the production of a novel metallo-β-lactamase (MBL), named SMB-1 (Serratia metallo-β-lactamase). SMB-1 possessed a zinc binding motif...

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Bibliographische Detailangaben
Hauptverfasser: Wachino, Jun-ichi, Yoshida, Hiroyuki, Yamane, Kunikazu, Suzuki, Satowa, Matsui, Mari, Yamagishi, Takuya, Tsutsui, Atsuko, Konda, Toshifumi, Shibayama, Keigo, Arakawa, Yoshichika
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195065/
https://ncbi.nlm.nih.gov/pubmed/21876060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05045-11
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