Fatal Outcome of Pandemic H1N1 2009 Influenza Virus Infection Is Associated with Immunopathology and Impaired Lung Repair, Not Enhanced Viral Burden, in Pregnant Mice

Pandemic A (H1N1) 2009 influenza virus (pH1N1) infection in pregnant women can be severe. The mechanisms that affect infection outcome in this population are not well understood. To address this, pregnant and nonpregnant BALB/c mice were inoculated with the wild-type pH1N1 strain A/California/04/09....

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Détails bibliographiques
Auteurs principaux: Marcelin, Glendie, Aldridge, Jerry R., Duan, Susu, Ghoneim, Hazem E., Rehg, Jerold, Marjuki, Henju, Boon, Adrianus C. M., McCullers, Jonathan A., Webby, Richard J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194964/
https://ncbi.nlm.nih.gov/pubmed/21865394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00654-11
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