Fatal Outcome of Pandemic H1N1 2009 Influenza Virus Infection Is Associated with Immunopathology and Impaired Lung Repair, Not Enhanced Viral Burden, in Pregnant Mice

Pandemic A (H1N1) 2009 influenza virus (pH1N1) infection in pregnant women can be severe. The mechanisms that affect infection outcome in this population are not well understood. To address this, pregnant and nonpregnant BALB/c mice were inoculated with the wild-type pH1N1 strain A/California/04/09....

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Detalhes bibliográficos
Main Authors: Marcelin, Glendie, Aldridge, Jerry R., Duan, Susu, Ghoneim, Hazem E., Rehg, Jerold, Marjuki, Henju, Boon, Adrianus C. M., McCullers, Jonathan A., Webby, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194964/
https://ncbi.nlm.nih.gov/pubmed/21865394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00654-11
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