Changes in H5N1 influenza virus hemagglutinin receptor binding domain affect systemic spread

The HA of influenza virus is a receptor-binding and fusion protein that is required to initiate infection. The HA receptor-binding domain determines the species of sialyl receptors recognized by influenza viruses. Here, we demonstrate that changes in the HA receptor-binding domain alter the ability...

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Bibliographische Detailangaben
Hauptverfasser: Yen, Hui-Ling, Aldridge, Jerry R., Boon, Adrianus C. M., Ilyushina, Natalia A., Salomon, Rachelle, Hulse-Post, Diane J., Marjuki, Henju, Franks, John, Boltz, David A., Bush, Dorothy, Lipatov, Aleksandr S., Webby, Richard J., Rehg, Jerold E., Webster, Robert G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629220/
https://ncbi.nlm.nih.gov/pubmed/19116267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811052106
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