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Protective immunity against the gastrointestinal nematode Nippostrongylus brasiliensis requires a broad T-cell receptor repertoire

The parasitic gastrointestinal nematode Nippostrongylus brasiliensis induces massive expansion of T helper type 2 (Th2) cells in the lung and small intestine. Th2 cells are a major source of interleukin-4 and interleukin-13, two cytokines that appear essential for rapid worm expulsion. It is unclear...

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Detalhes bibliográficos
Main Authors: Seidl, Alexander, Panzer, Marc, Voehringer, David
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194228/
https://ncbi.nlm.nih.gov/pubmed/21896015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03480.x
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