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Brain distribution and elimination of recombinant human TIMP-1 after cerebral ischemia and reperfusion in rats
OBJECTIVE: To investigate recombinant human TIMP-1 ((125)I-rhTIMP-1) half-life in blood and its distribution in rat brain tissue after cerebral ischemia/reperfusion as part of a therapeutic development paradigm. METHOD: A suture model of the middle cerebral artery occlusion was used. (125)I-labeled...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193946/ https://ncbi.nlm.nih.gov/pubmed/21535944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/1743132810Y.0000000012 |
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