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Induction of proliferation and differentiation of neoplastic B cells by anti-immunoglobulin and T-cell factors.

Sepharose-bound anti-immunoglobulins, which are potent mitogens for normal adult B cells, are not mitogenic for tumor cells freshly isolated from mice carrying the B-cell leukemia BCL1. However, after 4 or more days of in vitro cultivation, BCL1 cells can be stimulated to divide by either anti-mu or...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Isakson, P C, Puré, E, Uhr, J W, Vitetta, E S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1981
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319376/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6787608/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2507
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