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Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1).

Human macrophages produce in culture a factor termed mononuclear cell factor (MCF) that increases the production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells. A factor with similar biologic activity is also produced by the murine macrophage cell line P388D1. By us...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mizel, S B, Dayer, J M, Krane, S M, Mergenhagen, S E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1981
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC319369/
https://ncbi.nlm.nih.gov/pubmed/6264478
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