Base substitution in an intervening sequence of a beta+-thalassemic human globin gene.

beta globin gene fragments from a patient with homozygous beta+-thalassemia have been cloned and subjected to restriction endonuclease, nucleotide sequence, and in vitro trancription analyses. Restriction endonuclease mapping of the cloned gene fragments revealed no deletions or other rearrangements...

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Autori principali: Spritz, R A, Jagadeeswaran, P, Choudary, P V, Biro, P A, Elder, J T, deRiel, J K, Manley, J L, Gefter, M L, Forget, B G, Weissman, S M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1981
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC319365/
https://ncbi.nlm.nih.gov/pubmed/6264477
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