Base substitution in an intervening sequence of a beta+-thalassemic human globin gene.

beta globin gene fragments from a patient with homozygous beta+-thalassemia have been cloned and subjected to restriction endonuclease, nucleotide sequence, and in vitro trancription analyses. Restriction endonuclease mapping of the cloned gene fragments revealed no deletions or other rearrangements...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Spritz, R A, Jagadeeswaran, P, Choudary, P V, Biro, P A, Elder, J T, deRiel, J K, Manley, J L, Gefter, M L, Forget, B G, Weissman, S M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1981
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319365/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2455
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