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Structure of a rearranged gamma 1 chain gene and its implication to immunoglobulin class-switch mechanism.

An expressed gene for gamma 1 chain of MC 101 myeloma was cloned from a phage library containing partial EcoRI digests of MC 101 DNA. The cloned DNA was analyzed by restriction enzyme cleavage, Southern blot hybridization, R-loop formation, and nucleotide sequence determination. The results indicate...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Obata, M, Kataoka, T, Nakai, S, Yamagishi, H, Takahashi, N, Yamawaki-Kataoka, Y, Nikaido, T, Shimizu, A, Honjo, T
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6787603/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2437
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