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Nucleotide sequence and properties of the murine gamma 3 immunoglobulin heavy chain gene switch region: implications for successive C gamma gene switching.

During B lymphocyte differentiation, immunoglobulin heavy chain constant region (CH) genes undergo a unique series of DNA recombination events culminating in the CH class switch. CH switch (S) regions are located 2 kb 5' of each CH gene except delta (i.e. mu, gamma 3, gamma 1, gamma 2b, gamma 2...

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Autors principals: Stanton, L W, Marcu, K B
Format: Artigo
Idioma:Inglês
Publicat: 1982
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC320945/
https://ncbi.nlm.nih.gov/pubmed/6292864
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