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Riboswitches: discovery of drugs that target bacterial gene-regulatory RNAs
Riboswitches, which were discovered in the first years of the XXI century, are gene-regulatory mRNA domains that respond to the intracellular concentration of a variety of metabolites and second messengers. They control essential genes in many pathogenic bacteria, and represent a new class of biomol...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193592/ https://ncbi.nlm.nih.gov/pubmed/21615107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar200039b |
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